Engineered prime editors with PAM flexibility

Although prime editors are a powerful tool for genome editing, which can generate various types of mutations such as nucleotide substitutions, insertions, and deletions in the genome without double-strand breaks or donor DNA, the conventional prime editors are still limited to their target scopes be...

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Detalles Bibliográficos
Autores principales: Kweon, Jiyeon, Yoon, Jung-Ki, Jang, An-Hee, Shin, Ha Rim, See, Ji-Eun, Jang, Gayoung, Kim, Jong-Il, Kim, Yongsub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178456/
https://www.ncbi.nlm.nih.gov/pubmed/33636398
http://dx.doi.org/10.1016/j.ymthe.2021.02.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178456/
https://www.ncbi.nlm.nih.gov/pubmed/33636398
http://dx.doi.org/10.1016/j.ymthe.2021.02.022

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