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Trametinib therapy for children with neurofibromatosis type 1 and life‐threatening plexiform neurofibroma or treatment‐refractory low‐grade glioma
PURPOSE: To describe a series of children with extensive PNF or treatment refractory PLGG treated on a compassionate basis with trametinib. METHODS: We report on six patients with NF‐1 treated with trametinib on a compassionate basis at British Columbia Children's Hospital since 2017. Data were...
Autores principales: | Ronsley, Rebecca, Hounjet, Celine D., Cheng, Sylvia, Rassekh, Shahrad Rod, Duncan, Walter J., Dunham, Christopher, Gardiner, Jane, Ghag, Arvindera, Ludemann, Jeffrey P., Wensley, David, Rehmus, Wingfield, Sargent, Michael A., Hukin, Juliette |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178485/ https://www.ncbi.nlm.nih.gov/pubmed/33939292 http://dx.doi.org/10.1002/cam4.3910 |
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