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Selective Inhibition of 11β-Hydroxysteroid Dehydrogenase Type 1 Attenuates High-Fat Diet-Induced Hepatic Steatosis in Mice

INTRODUCTION: The effect of 11β-hydroxysteroid dehydrogenase type1 (11β-HSD1) inhibition on hepatic steatosis is incompletely understood. Here, we aimed to determine the therapeutic effect of BVT.2733, a selective 11β-HSD1 inhibitor, on hepatic steatosis. MATERIALS AND METHODS: C57B/6J mice were ran...

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Detalles Bibliográficos
Autores principales:	Li, Huashan, Sheng, Jianying, Wang, Jing, Gao, Haiting, Yu, Jing, Ding, Guoxian, Ding, Ning, He, Weiqi, Zha, Juanmin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178584/ https://www.ncbi.nlm.nih.gov/pubmed/34103895 http://dx.doi.org/10.2147/DDDT.S285828

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