Ultrasensitive small molecule fluorogenic probe for human heparanase

Heparanase (HPA) is a critical enzyme involved in the remodeling of the extracellular matrix (ECM), and its elevated expression has been linked with diseases such as various types of cancer and inflammation. The detection of heparanase enzymatic activity holds tremendous value in the study of the ce...

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Detalles Bibliográficos
Autores principales: Liu, Jun, Schleyer, Kelton A., Bryan, Tyrel L., Xie, Changjian, Seabra, Gustavo, Xu, Yongmei, Kafle, Arjun, Cui, Chao, Wang, Ying, Yin, Kunlun, Fetrow, Benjamin, Henderson, Paul K. P., Fatland, Peter Z., Liu, Jian, Li, Chenglong, Guo, Hua, Cui, Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178809/
https://www.ncbi.nlm.nih.gov/pubmed/34163592
http://dx.doi.org/10.1039/d0sc04872k

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