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Exposure to hypoxia causes stress erythropoiesis and downregulates immune response genes in spleen of mice
BACKGROUND: The spleen is the largest secondary lymphoid organ and the main site where stress erythropoiesis occurs. It is known that hypoxia triggers the expansion of erythroid progenitors; however, its effects on splenic gene expression are still unclear. Here, we examined splenic global gene expr...
Autores principales: | Wang, Haijing, Liu, Daoxin, Song, Pengfei, Jiang, Feng, Chi, Xiangwen, Zhang, Tongzuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178839/ https://www.ncbi.nlm.nih.gov/pubmed/34090336 http://dx.doi.org/10.1186/s12864-021-07731-x |
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