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Exposure to hypoxia causes stress erythropoiesis and downregulates immune response genes in spleen of mice

BACKGROUND: The spleen is the largest secondary lymphoid organ and the main site where stress erythropoiesis occurs. It is known that hypoxia triggers the expansion of erythroid progenitors; however, its effects on splenic gene expression are still unclear. Here, we examined splenic global gene expr...

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Detalles Bibliográficos
Autores principales: Wang, Haijing, Liu, Daoxin, Song, Pengfei, Jiang, Feng, Chi, Xiangwen, Zhang, Tongzuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178839/
https://www.ncbi.nlm.nih.gov/pubmed/34090336
http://dx.doi.org/10.1186/s12864-021-07731-x

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