Matrine suppresses cell growth of diffuse large B-cell lymphoma via inhibiting CaMKIIγ/c-Myc/CDK6 signaling pathway

BACKGROUND: C-Myc aberrations confer a more aggressive clinic behavior in diffuse large B-cell lymphoma (DLBCL). Matrine is an alkaloid extracted from Sophora flavescens Ait. It possesses anti-cancer property through inhibiting the cell proliferation and inducing the apoptosis. The present study aim...

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Detalles Bibliográficos
Autores principales: Gu, Jianyou, Wang, Xiao, Zhang, Ling, Xiang, Jingjing, Li, Jingya, Chen, Zheng, Zhang, Yu, Chen, Junfa, Shen, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178855/
https://www.ncbi.nlm.nih.gov/pubmed/34088288
http://dx.doi.org/10.1186/s12906-021-03315-0

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