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Interaction of 8-anilinonaphthalene-1-sulfonate with SARS-CoV-2 main protease and its application as a fluorescent probe for inhibitor identification
The 3C-like main protease of SARS-CoV-2 (3CL(Pro)) is responsible for the cleavage of the viral polyprotein. This process is essential for the viral life cycle. Therefore, 3CL(Pro) is a promising target to develop antiviral drugs for COVID-19 prevention and treatment. Traditional enzymatic assays fo...
Autores principales: | Deetanya, Peerapon, Hengphasatporn, Kowit, Wilasluck, Patcharin, Shigeta, Yasuteru, Rungrotmongkol, Thanyada, Wangkanont, Kittikhun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178945/ https://www.ncbi.nlm.nih.gov/pubmed/34109016 http://dx.doi.org/10.1016/j.csbj.2021.05.053 |
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