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Biomimetic hydrogen-bonding cascade for chemical activation: telling a nucleophile from a base

Hydrogen bonding-assisted polarization is an effective strategy to promote bond-making and bond-breaking chemical reactions. Taking inspiration from the catalytic triad of serine protease active sites, we have devised a conformationally well-defined benzimidazole platform that can be systematically...

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Detalles Bibliográficos
Autores principales: Park, Hyunchang, Lee, Dongwhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178988/
https://www.ncbi.nlm.nih.gov/pubmed/34163789
http://dx.doi.org/10.1039/d0sc05067a

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