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Small peptide diversification through photoredox-catalyzed oxidative C-terminal modification
A photoredox-catalyzed oxidative decarboxylative coupling of small peptides is reported, giving access to a variety of N,O-acetals. They were used as intermediates for the addition of phenols and indoles, leading to novel peptide scaffolds and bioconjugates. Amino acids with nucleophilic side chains...
Autores principales: | Le Du, Eliott, Garreau, Marion, Waser, Jérôme |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179259/ https://www.ncbi.nlm.nih.gov/pubmed/34164012 http://dx.doi.org/10.1039/d0sc06180h |
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