Cargando…
Traceless parallel peptide purification by a first-in-class reductively cleavable linker system featuring a safety-release
Hundreds of peptides can be synthesized by automated parallel synthesizers in a single run. In contrast, the most widely used peptide purification method – high-pressure liquid chromatography (HPLC) – only allows one-by-one processing of each sample. The chromatographic purification of many peptides...
Autores principales: | Zitterbart, Robert, Berger, Nadja, Reimann, Oliver, Noble, Gavin T., Lüdtke, Stephan, Sarma, Dominik, Seitz, Oliver |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179278/ https://www.ncbi.nlm.nih.gov/pubmed/34164003 http://dx.doi.org/10.1039/d0sc06285e |
Ejemplares similares
-
Cancer‐Cell‐Specific Drug Delivery by a Tumor‐Homing CPP‐Gossypol Conjugate Employing a Tracelessly Cleavable Linker
por: Maity, Suman Kumar, et al.
Publicado: (2020) -
Metal‐Free Aryl Cross‐Coupling Directed by Traceless Linkers
por: Haensch, Veit G., et al.
Publicado: (2019) -
Sulfatase-cleavable linkers for antibody-drug conjugates
por: Bargh, Jonathan D., et al.
Publicado: (2020) -
Peroxide-cleavable linkers for antibody–drug conjugates
por: Ashman, Nicola, et al.
Publicado: (2023) -
Lysosomal-Cleavable Peptide Linkers in Antibody–Drug Conjugates
por: Balamkundu, Seetharamsing, et al.
Publicado: (2023)