Mechanochemical reactivity inhibited, prohibited and reversed by liquid additives: examples from crystal-form screens

We demonstrate that liquid additives can exert inhibitive or prohibitive effects on the mechanochemical formation of multi-component molecular crystals, and report that certain additives unexpectedly prompt the dismantling of such solids into physical mixtures of their constituents. Computational me...

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Detalles Bibliográficos
Autores principales: Arhangelskis, Mihails, Bučar, Dejan-Krešimir, Bordignon, Simone, Chierotti, Michele R., Stratford, Samuel A., Voinovich, Dario, Jones, William, Hasa, Dritan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179350/
https://www.ncbi.nlm.nih.gov/pubmed/34164095
http://dx.doi.org/10.1039/d0sc05071g
Descripción
Sumario:We demonstrate that liquid additives can exert inhibitive or prohibitive effects on the mechanochemical formation of multi-component molecular crystals, and report that certain additives unexpectedly prompt the dismantling of such solids into physical mixtures of their constituents. Computational methods were employed in an attempt to identify possible reasons for these previously unrecognised effects of liquid additives on mechanochemical transformations.

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