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Single molecule force spectroscopy reveals the context dependent folding pathway of the C-terminal fragment of Top7
Top7 is a de novo designed protein with atomic level accuracy and shows a folded structure not found in nature. Previous studies showed that the folding of Top7 is not cooperative and involves various folding intermediate states. In addition, various fragments of Top7 were found to fold on their own...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179357/ https://www.ncbi.nlm.nih.gov/pubmed/34164053 http://dx.doi.org/10.1039/d0sc06344d |