An explicitly designed paratope of amyloid-β prevents neuronal apoptosis in vitro and hippocampal damage in rat brain

Synthetic antibodies hold great promise in combating diseases, diagnosis, and a wide range of biomedical applications. However, designing a therapeutically amenable, synthetic antibody that can arrest the aggregation of amyloid-β (Aβ) remains challenging. Here, we report a flexible, hairpin-like syn...

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Detalles Bibliográficos
Autores principales: Paul, Ashim, Kumar, Sourav, Kalita, Sujan, Kalita, Sourav, Sarkar, Dibakar, Bhunia, Anirban, Bandyopadhyay, Anupam, Mondal, Amal Chandra, Mandal, Bhubaneswar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179358/
https://www.ncbi.nlm.nih.gov/pubmed/34164050
http://dx.doi.org/10.1039/d0sc04379f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179358/
https://www.ncbi.nlm.nih.gov/pubmed/34164050
http://dx.doi.org/10.1039/d0sc04379f

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