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New directions of activity-based sensing for in vivo NIR imaging

In vivo imaging is a powerful approach to study biological processes. Beyond cellular methods, in vivo studies allow for biological stimuli (small molecules or proteins) to be studied in their native environment. This has the potential to aid in the discovery of new biology and guide the development...

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Detalles Bibliográficos
Autores principales: East, Amanda K., Lucero, Melissa Y., Chan, Jefferson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179399/
https://www.ncbi.nlm.nih.gov/pubmed/34163614
http://dx.doi.org/10.1039/d0sc03096a
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author East, Amanda K.
Lucero, Melissa Y.
Chan, Jefferson
author_facet East, Amanda K.
Lucero, Melissa Y.
Chan, Jefferson
author_sort East, Amanda K.
collection PubMed
description In vivo imaging is a powerful approach to study biological processes. Beyond cellular methods, in vivo studies allow for biological stimuli (small molecules or proteins) to be studied in their native environment. This has the potential to aid in the discovery of new biology and guide the development of diagnostics and therapies for diseases. To ensure selectivity and an observable readout, the probe development field is shifting towards activity-based sensing (ABS) approaches and near-infrared (NIR) imaging modalities. This perspective will highlight recent in vivo ABS applications that utilize NIR imaging platforms.
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spelling pubmed-81793992021-06-22 New directions of activity-based sensing for in vivo NIR imaging East, Amanda K. Lucero, Melissa Y. Chan, Jefferson Chem Sci Chemistry In vivo imaging is a powerful approach to study biological processes. Beyond cellular methods, in vivo studies allow for biological stimuli (small molecules or proteins) to be studied in their native environment. This has the potential to aid in the discovery of new biology and guide the development of diagnostics and therapies for diseases. To ensure selectivity and an observable readout, the probe development field is shifting towards activity-based sensing (ABS) approaches and near-infrared (NIR) imaging modalities. This perspective will highlight recent in vivo ABS applications that utilize NIR imaging platforms. The Royal Society of Chemistry 2020-07-03 /pmc/articles/PMC8179399/ /pubmed/34163614 http://dx.doi.org/10.1039/d0sc03096a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
East, Amanda K.
Lucero, Melissa Y.
Chan, Jefferson
New directions of activity-based sensing for in vivo NIR imaging
title New directions of activity-based sensing for in vivo NIR imaging
title_full New directions of activity-based sensing for in vivo NIR imaging
title_fullStr New directions of activity-based sensing for in vivo NIR imaging
title_full_unstemmed New directions of activity-based sensing for in vivo NIR imaging
title_short New directions of activity-based sensing for in vivo NIR imaging
title_sort new directions of activity-based sensing for in vivo nir imaging
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179399/
https://www.ncbi.nlm.nih.gov/pubmed/34163614
http://dx.doi.org/10.1039/d0sc03096a
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