Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes

Sulfonyl-triazoles are a new class of electrophiles that mediate covalent reaction with tyrosine residues on proteins through sulfur-triazole exchange (SuTEx) chemistry. Recent studies demonstrate the broad utility and tunability of SuTEx chemistry for chemical proteomics and protein ligand discover...

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Detalles Bibliográficos
Autores principales: Huang, Tao, Hosseinibarkooie, Seyyedmohsen, Borne, Adam L., Granade, Mitchell E., Brulet, Jeffrey W., Harris, Thurl E., Ferris, Heather A., Hsu, Ku-Lung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179411/
https://www.ncbi.nlm.nih.gov/pubmed/34164099
http://dx.doi.org/10.1039/d0sc06623k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179411/
https://www.ncbi.nlm.nih.gov/pubmed/34164099
http://dx.doi.org/10.1039/d0sc06623k

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