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Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes
Sulfonyl-triazoles are a new class of electrophiles that mediate covalent reaction with tyrosine residues on proteins through sulfur-triazole exchange (SuTEx) chemistry. Recent studies demonstrate the broad utility and tunability of SuTEx chemistry for chemical proteomics and protein ligand discover...
Autores principales: | Huang, Tao, Hosseinibarkooie, Seyyedmohsen, Borne, Adam L., Granade, Mitchell E., Brulet, Jeffrey W., Harris, Thurl E., Ferris, Heather A., Hsu, Ku-Lung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179411/ https://www.ncbi.nlm.nih.gov/pubmed/34164099 http://dx.doi.org/10.1039/d0sc06623k |
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