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Universal and high-fidelity DNA single nucleotide polymorphism detection based on a CRISPR/Cas12a biochip

Single nucleotide polymorphisms (SNPs) are associated with many human diseases, so accurate and efficient SNP detection is of great significance for early diagnosis and clinical prognosis. This report proposes a universal and high-fidelity genotyping method in microfluidic point-of-care equipment ba...

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Detalles Bibliográficos
Autores principales: Chen, Yong, Mei, Yixin, Jiang, Xingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179484/
https://www.ncbi.nlm.nih.gov/pubmed/34163711
http://dx.doi.org/10.1039/d0sc05717g