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Universal and high-fidelity DNA single nucleotide polymorphism detection based on a CRISPR/Cas12a biochip
Single nucleotide polymorphisms (SNPs) are associated with many human diseases, so accurate and efficient SNP detection is of great significance for early diagnosis and clinical prognosis. This report proposes a universal and high-fidelity genotyping method in microfluidic point-of-care equipment ba...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179484/ https://www.ncbi.nlm.nih.gov/pubmed/34163711 http://dx.doi.org/10.1039/d0sc05717g |