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New insights into the disulfide bond formation enzymes in epidithiodiketopiperazine alkaloids

Epidithiodiketopiperazines (ETPs) are a group of bioactive fungal natural products and structurally feature unique transannular disulfide bridges between α, α or α, β carbons. However, no enzyme has yet been demonstrated to catalyse α, β-disulfide bond formation in these molecules. Through genome mi...

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Detalles Bibliográficos
Autores principales:	Liu, Huan, Fan, Jie, Zhang, Peng, Hu, Youcai, Liu, Xingzhong, Li, Shu-Ming, Yin, Wen-Bing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179532/ https://www.ncbi.nlm.nih.gov/pubmed/34163685 http://dx.doi.org/10.1039/d0sc06647h

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