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Facile synthesis of axially chiral styrene-type carboxylic acids via palladium-catalyzed asymmetric C–H activation

A novel method by a one-step introduction of axial chirality and sterically hindered group has been developed for facile synthesis of axially chiral styrene-type carboxylic acids. With the palladium-catalyzed C–H arylation and olefination of readily available cinnamic acid established, this transfor...

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Detalles Bibliográficos
Autores principales: Yang, Chi, Wu, Tian-Rui, Li, Yan, Wu, Bing-Bing, Jin, Ruo-Xing, Hu, Duo-Duo, Li, Yuan-Bo, Bian, Kang-Jie, Wang, Xi-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179534/
https://www.ncbi.nlm.nih.gov/pubmed/34163646
http://dx.doi.org/10.1039/d0sc06661c