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Symmetry-related residues as promising hotspots for the evolution of de novo oligomeric enzymes
Directed evolution has provided us with great opportunities and prospects in the synthesis of tailor-made proteins. It, however, often requires at least mid to high throughput screening, necessitating more effective strategies for laboratory evolution. We herein demonstrate that protein symmetry can...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179601/ https://www.ncbi.nlm.nih.gov/pubmed/34168770 http://dx.doi.org/10.1039/d0sc06823c |