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Metabolic mechanisms of a drug revealed by distortion-free (13)C tracer analysis
Metabolomic isotopic tracing can provide flux information useful for understanding drug mechanisms. For that, NMR has the unique advantage of giving positional isotope enrichment information, but the current (13)C 1D NMR approach suffers from low sensitivity and high overlaps. We developed a new 2D...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179602/ https://www.ncbi.nlm.nih.gov/pubmed/34168765 http://dx.doi.org/10.1039/d0sc06480g |