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Catalytic asymmetric synthesis of N-substituted tetrahydroquinoxalines via regioselective Heyns rearrangement and stereoselective transfer hydrogenation in one pot
N-Substituted tetrahydroquinoxalines (37 examples) were step-economically obtained in good yield (<97%) and ee (<99%) with readily available substrates. The reaction proceeds through an interesting regioselective Heyns rearrangement/enantioselective transfer hydrogenation in one pot. The subst...
Autores principales: | Huang, Jin, Li, Guang-xun, Yang, Gao-feng, Fu, Ding-qiang, Nie, Xiao-kang, Cui, Xin, Zhao, Jin-zhong, Tang, Zhuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179646/ https://www.ncbi.nlm.nih.gov/pubmed/34168757 http://dx.doi.org/10.1039/d0sc06264b |
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