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Emergent synthetic methods for the modular advancement of sp(3)-rich fragments
Fragment-based drug discovery is an important and increasingly reliable technology for the delivery of clinical candidates. Notably, however, sp(3)-rich fragments are a largely untapped resource in molecular discovery, in part due to the lack of general and suitably robust chemical methods available...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Royal Society of Chemistry
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179648/ https://www.ncbi.nlm.nih.gov/pubmed/34168751 http://dx.doi.org/10.1039/d1sc00161b |