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Folate metabolism: a re-emerging therapeutic target in haematological cancers

Folate-mediated one carbon (1C) metabolism supports a series of processes that are essential for the cell. Through a number of interlinked reactions happening in the cytosol and mitochondria of the cell, folate metabolism contributes to de novo purine and thymidylate synthesis, to the methionine cyc...

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Detalles Bibliográficos
Autores principales:	Zarou, Martha M., Vazquez, Alexei, Vignir Helgason, G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179844/ https://www.ncbi.nlm.nih.gov/pubmed/33707653 http://dx.doi.org/10.1038/s41375-021-01189-2

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