Xenograft and cell culture models of Sézary syndrome reveal cell of origin diversity and subclonal heterogeneity

Sézary Syndrome (SS) is a rare aggressive epidermotropic cutaneous T-cell lymphoma (CTCL) defined by erythroderma, pruritis, and a circulating atypical CD4 + T-cell clonal population. The diversity of Sézary cell (SC) phenotype and genotype may reflect either plasticity or heterogeneity, which was d...

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Detalles Bibliográficos
Autores principales: Poglio, Sandrine, Prochazkova-Carlotti, Martina, Cherrier, Floriane, Gros, Audrey, Laharanne, Elodie, Pham-Ledard, Anne, Beylot-Barry, Marie, Merlio, Jean-Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179845/
https://www.ncbi.nlm.nih.gov/pubmed/33106625
http://dx.doi.org/10.1038/s41375-020-01068-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179845/
https://www.ncbi.nlm.nih.gov/pubmed/33106625
http://dx.doi.org/10.1038/s41375-020-01068-2

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