Cargando…

Xenograft and cell culture models of Sézary syndrome reveal cell of origin diversity and subclonal heterogeneity

Sézary Syndrome (SS) is a rare aggressive epidermotropic cutaneous T-cell lymphoma (CTCL) defined by erythroderma, pruritis, and a circulating atypical CD4 + T-cell clonal population. The diversity of Sézary cell (SC) phenotype and genotype may reflect either plasticity or heterogeneity, which was d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Poglio, Sandrine, Prochazkova-Carlotti, Martina, Cherrier, Floriane, Gros, Audrey, Laharanne, Elodie, Pham-Ledard, Anne, Beylot-Barry, Marie, Merlio, Jean-Philippe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179845/ https://www.ncbi.nlm.nih.gov/pubmed/33106625 http://dx.doi.org/10.1038/s41375-020-01068-2

Ejemplares similares

TP53 alterations in primary and secondary Sézary syndrome: A diagnostic tool for the assessment of malignancy in patients with erythroderma
por: Gros, Audrey, et al.
Publicado: (2017)

Targeting Epigenetic Modifiers Can Reduce the Clonogenic Capacities of Sézary Cells
por: Chebly, Alain, et al.
Publicado: (2021)

Exploring hTERT promoter methylation in cutaneous T‐cell lymphomas
por: Chebly, Alain, et al.
Publicado: (2021)

Molecular alterations and tumor suppressive function of the DUSP22 (Dual Specificity Phosphatase 22) gene in peripheral T-cell lymphoma subtypes
por: Mélard, Pierre, et al.
Publicado: (2016)

A High Programmed Cell Death Protein 1 Hormone Receptor Score on Skin Biopsy is Associated with Sézary Syndrome Diagnosis: A Study of 91 Patients with Erythroderma
por: LUHERNE, Camille, et al.
Publicado: (2022)

Speed of leukemia development and genetic diversity in xenograft models of T cell acute lymphoblastic leukemia
por: Poglio, Sandrine, et al.
Publicado: (2016)

Calcium Independent Effect of Orai1 and STIM1 in Non-Hodgkin B Cell Lymphoma Dissemination
por: Latour, Simon, et al.
Publicado: (2018)

Integrative diagnosis of primary cutaneous large B-cell lymphomas supports the relevance of cell of origin profiling
por: Gros, Audrey, et al.
Publicado: (2022)

Reliable blood cancer cells' telomere length evaluation by qPCR
por: Ropio, Joana, et al.
Publicado: (2020)

Telomeric Repeat-Containing RNA (TERRA): A Review of the Literature and First Assessment in Cutaneous T-Cell Lymphomas
por: Chebly, Alain, et al.
Publicado: (2022)

Spotlight on hTERT Complex Regulation in Cutaneous T-Cell Lymphomas
por: Ropio, Joana, et al.
Publicado: (2023)

Impact of blood involvement on efficacy and time to response with mogamulizumab in mycosis fungoides and Sézary syndrome
por: Beylot‐Barry, Marie, et al.
Publicado: (2022)

Subclonal heterogeneity and evolution in breast cancer
por: Mavrommati, Ioanna, et al.
Publicado: (2021)

Long-lasting cutaneous tuberculosis owing to Mycobacterium bovis masquerading as sarcoidosis
por: Dequidt, Laure, et al.
Publicado: (2018)

Tumor cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers
por: Cleary, Allison S., et al.
Publicado: (2014)

DENDRO: genetic heterogeneity profiling and subclone detection by single-cell RNA sequencing
por: Zhou, Zilu, et al.
Publicado: (2020)

The Cytolethal Distending Toxin Subunit CdtB of Helicobacter hepaticus Promotes Senescence and Endoreplication in Xenograft Mouse Models of Hepatic and Intestinal Cell Lines
por: Péré-Védrenne, Christelle, et al.
Publicado: (2017)

Successful rechallenge for severe lichenoid drug reaction to pembrolizumab presenting as “toxic epidermal necrolysis-like”
por: Eldani, Céline, et al.
Publicado: (2023)

Unravelling subclonal heterogeneity and aggressive disease states in TNBC through single-cell RNA-seq
por: Karaayvaz, Mihriban, et al.
Publicado: (2018)

Molecular profiling and specific targeting of gemcitabine-resistant subclones in heterogeneous pancreatic cancer cell populations
por: Färber, Benedikt, et al.
Publicado: (2023)

Alemtuzumab in refractory Sézary syndrome
por: Reifs, Carmen María Alcántara, et al.
Publicado: (2016)

Plantar keratoderma of Sézary syndrome
por: Fragkos, Konstantinos C.
Publicado: (2017)

Mycosis fungoides and Sézary syndrome
por: Jonak, Constanze, et al.
Publicado: (2021)

Mycosis fungoides and Sézary syndrome
por: Lee, Hyewon
Publicado: (2023)

Dupilumab-Associated Sezary Syndrome
por: Hamp, Austin, et al.
Publicado: (2023)

CD158k and PD-1 expressions define heterogeneous subtypes of Sezary syndrome
por: Vergnolle, Inès, et al.
Publicado: (2022)

DNA barcoding reveals diverse growth kinetics of human breast tumour subclones in serially passaged xenografts
por: Nguyen, Long V., et al.
Publicado: (2014)

Malignant subclone drives metastasis of genetically and phenotypically heterogenous cell clusters through fibrotic niche generation
por: Kok, Sau Yee, et al.
Publicado: (2021)

Single-cell RNA sequencing revealed subclonal heterogeneity and gene signatures of gemcitabine sensitivity in pancreatic cancer
por: Hou, Zelin, et al.
Publicado: (2023)

ALLOGENEIC HEMATOPOIETIC CELL TRANSPLANTATION FOR MYCOSIS FUNGOIDES AND SEZARY SYNDROME
por: Lechowicz, Mary Jo, et al.
Publicado: (2014)

Detecting copy number status and uncovering subclonal markers in heterogeneous tumor biopsies
por: Parisi, Fabio, et al.
Publicado: (2011)

Heterogeneity and proliferation of invasive cancer subclones in game theory models of the Warburg effect
por: Archetti, M.
Publicado: (2015)

Single-cell mRNA sequencing identifies subclonal heterogeneity in anti-cancer drug responses of lung adenocarcinoma cells
por: Kim, Kyu-Tae, et al.
Publicado: (2015)

Integrated Genomic Analysis of Sézary Syndrome
por: Mao, Xin, et al.
Publicado: (2011)

A mouse model for the Sézary syndrome
por: Doebbeling, Udo
Publicado: (2010)

Real-World Survival in Patients with Metastatic Melanoma after Discontinuation of Anti-PD-1 Immunotherapy for Objective Response or Adverse Effects: A Retrospective Study
por: Valentin, Julie, et al.
Publicado: (2021)

Gene Expression Comparison between Sézary Syndrome and Lymphocytic-Variant Hypereosinophilic Syndrome Refines Biomarkers for Sézary Syndrome
por: Moerman-Herzog, Andrea, et al.
Publicado: (2020)

Analysis of tumor response and clinical factors associated with vitiligo in patients receiving anti–programmed cell death-1 therapies for melanoma: A cross-sectional study
por: Dousset, Léa, et al.
Publicado: (2021)

Analytical subcloning of a clonal cell line demonstrates cellular heterogeneity that does not impact process consistency or robustness
por: Scarcelli, John J., et al.
Publicado: (2018)

Genetic rearrangements result in altered gene expression and novel fusion transcripts in Sézary syndrome
por: Przybylski, Grzegorz K., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_utv1m5f1e7uq4g80g8ut1dqub3