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Papel de cefditoreno en el tratamiento de las infecciones comunitarias de piel y tejidos blandos: revisando la evidencia

Cefditoren pivoxil is a third-generation oral cephalosporin with extended spectrum against gram-negative, gram-positive, and several anaerobic microorganisms, including those frequently implicated in skin and soft tissue infections (SSTI). Despite the fact that there are no approved breakpoint crite...

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Detalles Bibliográficos
Autores principales: Cabañero-Navalón, Marta Dafne, García-Bustos, Víctor, Lletí, Miguel Salavert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedad Española de Quimioterapia 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179948/
https://www.ncbi.nlm.nih.gov/pubmed/34027966
http://dx.doi.org/10.37201/req/063.2021
Descripción
Sumario:Cefditoren pivoxil is a third-generation oral cephalosporin with extended spectrum against gram-negative, gram-positive, and several anaerobic microorganisms, including those frequently implicated in skin and soft tissue infections (SSTI). Despite the fact that there are no approved breakpoint criteria for cefditoren susceptibility, many pharmacokinetic and pharmacodynamic studies reassert cefditoren as a good oral antibiotic for the treatment of SSTI. Regarding patients with SSTI, including those infections caused by Staphylococcus aureus y Streptococcus pyogenes, cefditoren showed high cure rates when compared to other oral cephalosporins.