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Nonspecific orbital inflammation and thyroid eye disease, a rare comorbidity: report of two cases and review of literature
BACKGROUND: To present the very rare comorbidity of developing non-specific orbital inflammation (NSOI) in two patients with histories of definite thyroid eye disease (TED). CASE PRESENTATION: Both patients complained of new-onset progressive proptosis although their thyroid disease was controlled a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180075/ https://www.ncbi.nlm.nih.gov/pubmed/34090378 http://dx.doi.org/10.1186/s12886-021-02008-z |
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author | Eshraghi, Bahram Dehghan, Amin Javadi, Niloofar Fazel, Mohammadreza |
author_facet | Eshraghi, Bahram Dehghan, Amin Javadi, Niloofar Fazel, Mohammadreza |
author_sort | Eshraghi, Bahram |
collection | PubMed |
description | BACKGROUND: To present the very rare comorbidity of developing non-specific orbital inflammation (NSOI) in two patients with histories of definite thyroid eye disease (TED). CASE PRESENTATION: Both patients complained of new-onset progressive proptosis although their thyroid disease was controlled and computed tomography scan revealed an intraorbital inflammatory mass. The pathological assessment indicated that both patients had developed fibrosing NSOI. Therefore, intravenous corticosteroids were administered. The mass regressed and the amount of proptosis was decreased in both patients. CONCLUSIONS: We reviewed all related cases in the literature and extracted their clinical and radiological characteristics for this paper. Ophthalmologists should consider TED and NSOI in patients with a new-onset complaint of proptosis. Despite rare comorbidity of TED and NSOI, it should be considered especially in patients with refractory proptosis, and lead to its further evaluation and prompt management. |
format | Online Article Text |
id | pubmed-8180075 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-81800752021-06-07 Nonspecific orbital inflammation and thyroid eye disease, a rare comorbidity: report of two cases and review of literature Eshraghi, Bahram Dehghan, Amin Javadi, Niloofar Fazel, Mohammadreza BMC Ophthalmol Case Report BACKGROUND: To present the very rare comorbidity of developing non-specific orbital inflammation (NSOI) in two patients with histories of definite thyroid eye disease (TED). CASE PRESENTATION: Both patients complained of new-onset progressive proptosis although their thyroid disease was controlled and computed tomography scan revealed an intraorbital inflammatory mass. The pathological assessment indicated that both patients had developed fibrosing NSOI. Therefore, intravenous corticosteroids were administered. The mass regressed and the amount of proptosis was decreased in both patients. CONCLUSIONS: We reviewed all related cases in the literature and extracted their clinical and radiological characteristics for this paper. Ophthalmologists should consider TED and NSOI in patients with a new-onset complaint of proptosis. Despite rare comorbidity of TED and NSOI, it should be considered especially in patients with refractory proptosis, and lead to its further evaluation and prompt management. BioMed Central 2021-06-05 /pmc/articles/PMC8180075/ /pubmed/34090378 http://dx.doi.org/10.1186/s12886-021-02008-z Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Case Report Eshraghi, Bahram Dehghan, Amin Javadi, Niloofar Fazel, Mohammadreza Nonspecific orbital inflammation and thyroid eye disease, a rare comorbidity: report of two cases and review of literature |
title | Nonspecific orbital inflammation and thyroid eye disease, a rare comorbidity: report of two cases and review of literature |
title_full | Nonspecific orbital inflammation and thyroid eye disease, a rare comorbidity: report of two cases and review of literature |
title_fullStr | Nonspecific orbital inflammation and thyroid eye disease, a rare comorbidity: report of two cases and review of literature |
title_full_unstemmed | Nonspecific orbital inflammation and thyroid eye disease, a rare comorbidity: report of two cases and review of literature |
title_short | Nonspecific orbital inflammation and thyroid eye disease, a rare comorbidity: report of two cases and review of literature |
title_sort | nonspecific orbital inflammation and thyroid eye disease, a rare comorbidity: report of two cases and review of literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180075/ https://www.ncbi.nlm.nih.gov/pubmed/34090378 http://dx.doi.org/10.1186/s12886-021-02008-z |
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