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Synapse-specific Lrp4 mRNA enrichment requires Lrp4/MuSK signaling, muscle activity and Wnt non-canonical pathway

BACKGROUND: The neuromuscular junction (NMJ) is a peripheral synapse critical to muscle contraction. Like acetylcholine receptors (AChRs), many essential proteins of NMJ are extremely concentrated at the postjunctional membrane. However, the mechanisms of synapse-specific concentration are not well...

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Detalles Bibliográficos
Autores principales: Jing, Hongyang, Chen, Peng, Hui, Tiankun, Yu, Zheng, Zhou, Jin, Fei, Erkang, Wang, Shunqi, Ren, Dongyan, Lai, Xinsheng, Li, Baoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180081/
https://www.ncbi.nlm.nih.gov/pubmed/34090516
http://dx.doi.org/10.1186/s13578-021-00619-z