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Synapse-specific Lrp4 mRNA enrichment requires Lrp4/MuSK signaling, muscle activity and Wnt non-canonical pathway
BACKGROUND: The neuromuscular junction (NMJ) is a peripheral synapse critical to muscle contraction. Like acetylcholine receptors (AChRs), many essential proteins of NMJ are extremely concentrated at the postjunctional membrane. However, the mechanisms of synapse-specific concentration are not well...
Autores principales: | Jing, Hongyang, Chen, Peng, Hui, Tiankun, Yu, Zheng, Zhou, Jin, Fei, Erkang, Wang, Shunqi, Ren, Dongyan, Lai, Xinsheng, Li, Baoming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180081/ https://www.ncbi.nlm.nih.gov/pubmed/34090516 http://dx.doi.org/10.1186/s13578-021-00619-z |
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