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SARS-CoV-2 reinfection with a virus harboring mutation in the Spike and the Nucleocapsid proteins in Panama

We report a case of reinfection by SARS-CoV-2 with the second virus harboring amino acid changes in the Spike protein (141-143del, D215A, ins215AGY, L452R, D614G), orf1a, helicase, orf3a, and Nucleocapside. The virus associated with the reinfection, from an endemic lineage containing the S:L452R imm...

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Autores principales: Díaz, Yamilka, Ortiz, Anyuri, Weeden, Adriana, Castillo, Daniel, González, Claudia, Moreno, Brechla, Martínez-Montero, Mabel, Castillo, Marlene, Vasquez, Grettel, Sáenz, Lisseth, Franco, Danilo, Pitti, Yaneth, Chavarria, Oris, Gondola, Jessica, Moreno, Ambar M., Ábrego, Leyda, Beltrán, Davis, Guerra, Ilka, Chang, Jim, Chaverra, Zumara, Guerrero, Isela, Valoy, Alejandra, Gaitán, Melissa, Araúz, Dimelza, Morán, Ernesto, Chen-Germán, Maria, Valdespino, Elimelec, Rodríguez, Rita, Corrales, Rita, Chen-Camaño, Roderick, Pascale, Juan Miguel, Martínez, Alexander A., López-Vergès, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180085/
https://www.ncbi.nlm.nih.gov/pubmed/34107326
http://dx.doi.org/10.1016/j.ijid.2021.06.004
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author Díaz, Yamilka
Ortiz, Anyuri
Weeden, Adriana
Castillo, Daniel
González, Claudia
Moreno, Brechla
Martínez-Montero, Mabel
Castillo, Marlene
Vasquez, Grettel
Sáenz, Lisseth
Franco, Danilo
Pitti, Yaneth
Chavarria, Oris
Gondola, Jessica
Moreno, Ambar M.
Ábrego, Leyda
Beltrán, Davis
Guerra, Ilka
Chang, Jim
Chaverra, Zumara
Guerrero, Isela
Valoy, Alejandra
Gaitán, Melissa
Araúz, Dimelza
Morán, Ernesto
Chen-Germán, Maria
Valdespino, Elimelec
Rodríguez, Rita
Corrales, Rita
Chen-Camaño, Roderick
Pascale, Juan Miguel
Martínez, Alexander A.
López-Vergès, Sandra
author_facet Díaz, Yamilka
Ortiz, Anyuri
Weeden, Adriana
Castillo, Daniel
González, Claudia
Moreno, Brechla
Martínez-Montero, Mabel
Castillo, Marlene
Vasquez, Grettel
Sáenz, Lisseth
Franco, Danilo
Pitti, Yaneth
Chavarria, Oris
Gondola, Jessica
Moreno, Ambar M.
Ábrego, Leyda
Beltrán, Davis
Guerra, Ilka
Chang, Jim
Chaverra, Zumara
Guerrero, Isela
Valoy, Alejandra
Gaitán, Melissa
Araúz, Dimelza
Morán, Ernesto
Chen-Germán, Maria
Valdespino, Elimelec
Rodríguez, Rita
Corrales, Rita
Chen-Camaño, Roderick
Pascale, Juan Miguel
Martínez, Alexander A.
López-Vergès, Sandra
author_sort Díaz, Yamilka
collection PubMed
description We report a case of reinfection by SARS-CoV-2 with the second virus harboring amino acid changes in the Spike protein (141-143del, D215A, ins215AGY, L452R, D614G), orf1a, helicase, orf3a, and Nucleocapside. The virus associated with the reinfection, from an endemic lineage containing the S:L452R immune escape mutation, was circulating in Panama at the time.
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spelling pubmed-81800852021-06-07 SARS-CoV-2 reinfection with a virus harboring mutation in the Spike and the Nucleocapsid proteins in Panama Díaz, Yamilka Ortiz, Anyuri Weeden, Adriana Castillo, Daniel González, Claudia Moreno, Brechla Martínez-Montero, Mabel Castillo, Marlene Vasquez, Grettel Sáenz, Lisseth Franco, Danilo Pitti, Yaneth Chavarria, Oris Gondola, Jessica Moreno, Ambar M. Ábrego, Leyda Beltrán, Davis Guerra, Ilka Chang, Jim Chaverra, Zumara Guerrero, Isela Valoy, Alejandra Gaitán, Melissa Araúz, Dimelza Morán, Ernesto Chen-Germán, Maria Valdespino, Elimelec Rodríguez, Rita Corrales, Rita Chen-Camaño, Roderick Pascale, Juan Miguel Martínez, Alexander A. López-Vergès, Sandra Int J Infect Dis Case Report We report a case of reinfection by SARS-CoV-2 with the second virus harboring amino acid changes in the Spike protein (141-143del, D215A, ins215AGY, L452R, D614G), orf1a, helicase, orf3a, and Nucleocapside. The virus associated with the reinfection, from an endemic lineage containing the S:L452R immune escape mutation, was circulating in Panama at the time. The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2021-07 2021-06-06 /pmc/articles/PMC8180085/ /pubmed/34107326 http://dx.doi.org/10.1016/j.ijid.2021.06.004 Text en © 2021 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Case Report
Díaz, Yamilka
Ortiz, Anyuri
Weeden, Adriana
Castillo, Daniel
González, Claudia
Moreno, Brechla
Martínez-Montero, Mabel
Castillo, Marlene
Vasquez, Grettel
Sáenz, Lisseth
Franco, Danilo
Pitti, Yaneth
Chavarria, Oris
Gondola, Jessica
Moreno, Ambar M.
Ábrego, Leyda
Beltrán, Davis
Guerra, Ilka
Chang, Jim
Chaverra, Zumara
Guerrero, Isela
Valoy, Alejandra
Gaitán, Melissa
Araúz, Dimelza
Morán, Ernesto
Chen-Germán, Maria
Valdespino, Elimelec
Rodríguez, Rita
Corrales, Rita
Chen-Camaño, Roderick
Pascale, Juan Miguel
Martínez, Alexander A.
López-Vergès, Sandra
SARS-CoV-2 reinfection with a virus harboring mutation in the Spike and the Nucleocapsid proteins in Panama
title SARS-CoV-2 reinfection with a virus harboring mutation in the Spike and the Nucleocapsid proteins in Panama
title_full SARS-CoV-2 reinfection with a virus harboring mutation in the Spike and the Nucleocapsid proteins in Panama
title_fullStr SARS-CoV-2 reinfection with a virus harboring mutation in the Spike and the Nucleocapsid proteins in Panama
title_full_unstemmed SARS-CoV-2 reinfection with a virus harboring mutation in the Spike and the Nucleocapsid proteins in Panama
title_short SARS-CoV-2 reinfection with a virus harboring mutation in the Spike and the Nucleocapsid proteins in Panama
title_sort sars-cov-2 reinfection with a virus harboring mutation in the spike and the nucleocapsid proteins in panama
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180085/
https://www.ncbi.nlm.nih.gov/pubmed/34107326
http://dx.doi.org/10.1016/j.ijid.2021.06.004
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