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SARS-CoV-2 reinfection with a virus harboring mutation in the Spike and the Nucleocapsid proteins in Panama
We report a case of reinfection by SARS-CoV-2 with the second virus harboring amino acid changes in the Spike protein (141-143del, D215A, ins215AGY, L452R, D614G), orf1a, helicase, orf3a, and Nucleocapside. The virus associated with the reinfection, from an endemic lineage containing the S:L452R imm...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180085/ https://www.ncbi.nlm.nih.gov/pubmed/34107326 http://dx.doi.org/10.1016/j.ijid.2021.06.004 |
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author | Díaz, Yamilka Ortiz, Anyuri Weeden, Adriana Castillo, Daniel González, Claudia Moreno, Brechla Martínez-Montero, Mabel Castillo, Marlene Vasquez, Grettel Sáenz, Lisseth Franco, Danilo Pitti, Yaneth Chavarria, Oris Gondola, Jessica Moreno, Ambar M. Ábrego, Leyda Beltrán, Davis Guerra, Ilka Chang, Jim Chaverra, Zumara Guerrero, Isela Valoy, Alejandra Gaitán, Melissa Araúz, Dimelza Morán, Ernesto Chen-Germán, Maria Valdespino, Elimelec Rodríguez, Rita Corrales, Rita Chen-Camaño, Roderick Pascale, Juan Miguel Martínez, Alexander A. López-Vergès, Sandra |
author_facet | Díaz, Yamilka Ortiz, Anyuri Weeden, Adriana Castillo, Daniel González, Claudia Moreno, Brechla Martínez-Montero, Mabel Castillo, Marlene Vasquez, Grettel Sáenz, Lisseth Franco, Danilo Pitti, Yaneth Chavarria, Oris Gondola, Jessica Moreno, Ambar M. Ábrego, Leyda Beltrán, Davis Guerra, Ilka Chang, Jim Chaverra, Zumara Guerrero, Isela Valoy, Alejandra Gaitán, Melissa Araúz, Dimelza Morán, Ernesto Chen-Germán, Maria Valdespino, Elimelec Rodríguez, Rita Corrales, Rita Chen-Camaño, Roderick Pascale, Juan Miguel Martínez, Alexander A. López-Vergès, Sandra |
author_sort | Díaz, Yamilka |
collection | PubMed |
description | We report a case of reinfection by SARS-CoV-2 with the second virus harboring amino acid changes in the Spike protein (141-143del, D215A, ins215AGY, L452R, D614G), orf1a, helicase, orf3a, and Nucleocapside. The virus associated with the reinfection, from an endemic lineage containing the S:L452R immune escape mutation, was circulating in Panama at the time. |
format | Online Article Text |
id | pubmed-8180085 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. |
record_format | MEDLINE/PubMed |
spelling | pubmed-81800852021-06-07 SARS-CoV-2 reinfection with a virus harboring mutation in the Spike and the Nucleocapsid proteins in Panama Díaz, Yamilka Ortiz, Anyuri Weeden, Adriana Castillo, Daniel González, Claudia Moreno, Brechla Martínez-Montero, Mabel Castillo, Marlene Vasquez, Grettel Sáenz, Lisseth Franco, Danilo Pitti, Yaneth Chavarria, Oris Gondola, Jessica Moreno, Ambar M. Ábrego, Leyda Beltrán, Davis Guerra, Ilka Chang, Jim Chaverra, Zumara Guerrero, Isela Valoy, Alejandra Gaitán, Melissa Araúz, Dimelza Morán, Ernesto Chen-Germán, Maria Valdespino, Elimelec Rodríguez, Rita Corrales, Rita Chen-Camaño, Roderick Pascale, Juan Miguel Martínez, Alexander A. López-Vergès, Sandra Int J Infect Dis Case Report We report a case of reinfection by SARS-CoV-2 with the second virus harboring amino acid changes in the Spike protein (141-143del, D215A, ins215AGY, L452R, D614G), orf1a, helicase, orf3a, and Nucleocapside. The virus associated with the reinfection, from an endemic lineage containing the S:L452R immune escape mutation, was circulating in Panama at the time. The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2021-07 2021-06-06 /pmc/articles/PMC8180085/ /pubmed/34107326 http://dx.doi.org/10.1016/j.ijid.2021.06.004 Text en © 2021 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Case Report Díaz, Yamilka Ortiz, Anyuri Weeden, Adriana Castillo, Daniel González, Claudia Moreno, Brechla Martínez-Montero, Mabel Castillo, Marlene Vasquez, Grettel Sáenz, Lisseth Franco, Danilo Pitti, Yaneth Chavarria, Oris Gondola, Jessica Moreno, Ambar M. Ábrego, Leyda Beltrán, Davis Guerra, Ilka Chang, Jim Chaverra, Zumara Guerrero, Isela Valoy, Alejandra Gaitán, Melissa Araúz, Dimelza Morán, Ernesto Chen-Germán, Maria Valdespino, Elimelec Rodríguez, Rita Corrales, Rita Chen-Camaño, Roderick Pascale, Juan Miguel Martínez, Alexander A. López-Vergès, Sandra SARS-CoV-2 reinfection with a virus harboring mutation in the Spike and the Nucleocapsid proteins in Panama |
title | SARS-CoV-2 reinfection with a virus harboring mutation in the Spike and the Nucleocapsid proteins in Panama |
title_full | SARS-CoV-2 reinfection with a virus harboring mutation in the Spike and the Nucleocapsid proteins in Panama |
title_fullStr | SARS-CoV-2 reinfection with a virus harboring mutation in the Spike and the Nucleocapsid proteins in Panama |
title_full_unstemmed | SARS-CoV-2 reinfection with a virus harboring mutation in the Spike and the Nucleocapsid proteins in Panama |
title_short | SARS-CoV-2 reinfection with a virus harboring mutation in the Spike and the Nucleocapsid proteins in Panama |
title_sort | sars-cov-2 reinfection with a virus harboring mutation in the spike and the nucleocapsid proteins in panama |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180085/ https://www.ncbi.nlm.nih.gov/pubmed/34107326 http://dx.doi.org/10.1016/j.ijid.2021.06.004 |
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