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Brain gray matter astroglia-specific connexin 43 ablation attenuates spinal cord inflammatory demyelination

BACKGROUND: Brain astroglia are activated preceding the onset of experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS). We characterized the effects of brain astroglia on spinal cord inflammation, focusing on astroglial connexin (Cx)43, because we recently repor...

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Detalles Bibliográficos
Autores principales: Une, Hayato, Yamasaki, Ryo, Nagata, Satoshi, Yamaguchi, Hiroo, Nakamuta, Yuko, Indiasari, Ulfa Camelia, Cui, Yiwen, Shinoda, Koji, Masaki, Katsuhisa, Götz, Magdalena, Kira, Jun-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180177/
https://www.ncbi.nlm.nih.gov/pubmed/34090477
http://dx.doi.org/10.1186/s12974-021-02176-1