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Brain gray matter astroglia-specific connexin 43 ablation attenuates spinal cord inflammatory demyelination
BACKGROUND: Brain astroglia are activated preceding the onset of experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS). We characterized the effects of brain astroglia on spinal cord inflammation, focusing on astroglial connexin (Cx)43, because we recently repor...
Autores principales: | Une, Hayato, Yamasaki, Ryo, Nagata, Satoshi, Yamaguchi, Hiroo, Nakamuta, Yuko, Indiasari, Ulfa Camelia, Cui, Yiwen, Shinoda, Koji, Masaki, Katsuhisa, Götz, Magdalena, Kira, Jun-ichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180177/ https://www.ncbi.nlm.nih.gov/pubmed/34090477 http://dx.doi.org/10.1186/s12974-021-02176-1 |
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