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Rehabilitation and pharmacotherapy of neuromyelitis optica spectrum disorder: A case report

BACKGROUND: Neuromyelitis optica spectrum disorder (NMOSD) is a demyelinating autoimmune disease that affects the central nervous system. It typically manifests as optic neuritis or extensive longitudinal myelitis, with or without the presence of anti-aquaporin protein 4 autoantibodies (immunoglobul...

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Autores principales: Wang, Xiao-Ju, Xia, Peng, Yang, Ting, Cheng, Kai, Chen, An-Liang, Li, Xue-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180214/
https://www.ncbi.nlm.nih.gov/pubmed/34141752
http://dx.doi.org/10.12998/wjcc.v9.i16.3951
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author Wang, Xiao-Ju
Xia, Peng
Yang, Ting
Cheng, Kai
Chen, An-Liang
Li, Xue-Ping
author_facet Wang, Xiao-Ju
Xia, Peng
Yang, Ting
Cheng, Kai
Chen, An-Liang
Li, Xue-Ping
author_sort Wang, Xiao-Ju
collection PubMed
description BACKGROUND: Neuromyelitis optica spectrum disorder (NMOSD) is a demyelinating autoimmune disease that affects the central nervous system. It typically manifests as optic neuritis or extensive longitudinal myelitis, with or without the presence of anti-aquaporin protein 4 autoantibodies (immunoglobulin G). CASE SUMMARY: We report the case of a 45-year-old woman with a history of Sjogren's syndrome who was diagnosed with NMOSD accompanied by spinal cord injury and left calf intermuscular vein thrombosis. The patient received hormone shock and gamma globulin therapy in the acute phase and standard rehabilitation treatment during convalescence. Upon discharge, the patient was able to control urination and defecation, stand independently, and walk short distances with the aid of a walker. CONCLUSION: This case suggests that pharmacotherapy and standard rehabilitation treatment can improve the prognosis of NMSOD patients.
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spelling pubmed-81802142021-06-16 Rehabilitation and pharmacotherapy of neuromyelitis optica spectrum disorder: A case report Wang, Xiao-Ju Xia, Peng Yang, Ting Cheng, Kai Chen, An-Liang Li, Xue-Ping World J Clin Cases Case Report BACKGROUND: Neuromyelitis optica spectrum disorder (NMOSD) is a demyelinating autoimmune disease that affects the central nervous system. It typically manifests as optic neuritis or extensive longitudinal myelitis, with or without the presence of anti-aquaporin protein 4 autoantibodies (immunoglobulin G). CASE SUMMARY: We report the case of a 45-year-old woman with a history of Sjogren's syndrome who was diagnosed with NMOSD accompanied by spinal cord injury and left calf intermuscular vein thrombosis. The patient received hormone shock and gamma globulin therapy in the acute phase and standard rehabilitation treatment during convalescence. Upon discharge, the patient was able to control urination and defecation, stand independently, and walk short distances with the aid of a walker. CONCLUSION: This case suggests that pharmacotherapy and standard rehabilitation treatment can improve the prognosis of NMSOD patients. Baishideng Publishing Group Inc 2021-06-06 2021-06-06 /pmc/articles/PMC8180214/ /pubmed/34141752 http://dx.doi.org/10.12998/wjcc.v9.i16.3951 Text en ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Case Report
Wang, Xiao-Ju
Xia, Peng
Yang, Ting
Cheng, Kai
Chen, An-Liang
Li, Xue-Ping
Rehabilitation and pharmacotherapy of neuromyelitis optica spectrum disorder: A case report
title Rehabilitation and pharmacotherapy of neuromyelitis optica spectrum disorder: A case report
title_full Rehabilitation and pharmacotherapy of neuromyelitis optica spectrum disorder: A case report
title_fullStr Rehabilitation and pharmacotherapy of neuromyelitis optica spectrum disorder: A case report
title_full_unstemmed Rehabilitation and pharmacotherapy of neuromyelitis optica spectrum disorder: A case report
title_short Rehabilitation and pharmacotherapy of neuromyelitis optica spectrum disorder: A case report
title_sort rehabilitation and pharmacotherapy of neuromyelitis optica spectrum disorder: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180214/
https://www.ncbi.nlm.nih.gov/pubmed/34141752
http://dx.doi.org/10.12998/wjcc.v9.i16.3951
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