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Rehabilitation and pharmacotherapy of neuromyelitis optica spectrum disorder: A case report
BACKGROUND: Neuromyelitis optica spectrum disorder (NMOSD) is a demyelinating autoimmune disease that affects the central nervous system. It typically manifests as optic neuritis or extensive longitudinal myelitis, with or without the presence of anti-aquaporin protein 4 autoantibodies (immunoglobul...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180214/ https://www.ncbi.nlm.nih.gov/pubmed/34141752 http://dx.doi.org/10.12998/wjcc.v9.i16.3951 |
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author | Wang, Xiao-Ju Xia, Peng Yang, Ting Cheng, Kai Chen, An-Liang Li, Xue-Ping |
author_facet | Wang, Xiao-Ju Xia, Peng Yang, Ting Cheng, Kai Chen, An-Liang Li, Xue-Ping |
author_sort | Wang, Xiao-Ju |
collection | PubMed |
description | BACKGROUND: Neuromyelitis optica spectrum disorder (NMOSD) is a demyelinating autoimmune disease that affects the central nervous system. It typically manifests as optic neuritis or extensive longitudinal myelitis, with or without the presence of anti-aquaporin protein 4 autoantibodies (immunoglobulin G). CASE SUMMARY: We report the case of a 45-year-old woman with a history of Sjogren's syndrome who was diagnosed with NMOSD accompanied by spinal cord injury and left calf intermuscular vein thrombosis. The patient received hormone shock and gamma globulin therapy in the acute phase and standard rehabilitation treatment during convalescence. Upon discharge, the patient was able to control urination and defecation, stand independently, and walk short distances with the aid of a walker. CONCLUSION: This case suggests that pharmacotherapy and standard rehabilitation treatment can improve the prognosis of NMSOD patients. |
format | Online Article Text |
id | pubmed-8180214 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-81802142021-06-16 Rehabilitation and pharmacotherapy of neuromyelitis optica spectrum disorder: A case report Wang, Xiao-Ju Xia, Peng Yang, Ting Cheng, Kai Chen, An-Liang Li, Xue-Ping World J Clin Cases Case Report BACKGROUND: Neuromyelitis optica spectrum disorder (NMOSD) is a demyelinating autoimmune disease that affects the central nervous system. It typically manifests as optic neuritis or extensive longitudinal myelitis, with or without the presence of anti-aquaporin protein 4 autoantibodies (immunoglobulin G). CASE SUMMARY: We report the case of a 45-year-old woman with a history of Sjogren's syndrome who was diagnosed with NMOSD accompanied by spinal cord injury and left calf intermuscular vein thrombosis. The patient received hormone shock and gamma globulin therapy in the acute phase and standard rehabilitation treatment during convalescence. Upon discharge, the patient was able to control urination and defecation, stand independently, and walk short distances with the aid of a walker. CONCLUSION: This case suggests that pharmacotherapy and standard rehabilitation treatment can improve the prognosis of NMSOD patients. Baishideng Publishing Group Inc 2021-06-06 2021-06-06 /pmc/articles/PMC8180214/ /pubmed/34141752 http://dx.doi.org/10.12998/wjcc.v9.i16.3951 Text en ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. |
spellingShingle | Case Report Wang, Xiao-Ju Xia, Peng Yang, Ting Cheng, Kai Chen, An-Liang Li, Xue-Ping Rehabilitation and pharmacotherapy of neuromyelitis optica spectrum disorder: A case report |
title | Rehabilitation and pharmacotherapy of neuromyelitis optica spectrum disorder: A case report |
title_full | Rehabilitation and pharmacotherapy of neuromyelitis optica spectrum disorder: A case report |
title_fullStr | Rehabilitation and pharmacotherapy of neuromyelitis optica spectrum disorder: A case report |
title_full_unstemmed | Rehabilitation and pharmacotherapy of neuromyelitis optica spectrum disorder: A case report |
title_short | Rehabilitation and pharmacotherapy of neuromyelitis optica spectrum disorder: A case report |
title_sort | rehabilitation and pharmacotherapy of neuromyelitis optica spectrum disorder: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180214/ https://www.ncbi.nlm.nih.gov/pubmed/34141752 http://dx.doi.org/10.12998/wjcc.v9.i16.3951 |
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