Cargando…

Cochlin Deficiency Protects Against Noise-Induced Hearing Loss

Cochlin is the most abundant protein in the inner ear. To study its function in response to noise trauma, we exposed adolescent wild-type (Coch(+/+)) and cochlin knock-out (Coch(–/–)) mice to noise (8–16 kHz, 103 dB SPL, 2 h) that causes a permanent threshold shift and hair cell loss. Two weeks afte...

Descripción completa

Detalles Bibliográficos
Autores principales: Seist, Richard, Landegger, Lukas D., Robertson, Nahid G., Vasilijic, Sasa, Morton, Cynthia C., Stankovic, Konstantina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180578/
https://www.ncbi.nlm.nih.gov/pubmed/34108864
http://dx.doi.org/10.3389/fnmol.2021.670013