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Cochlin Deficiency Protects Against Noise-Induced Hearing Loss
Cochlin is the most abundant protein in the inner ear. To study its function in response to noise trauma, we exposed adolescent wild-type (Coch(+/+)) and cochlin knock-out (Coch(–/–)) mice to noise (8–16 kHz, 103 dB SPL, 2 h) that causes a permanent threshold shift and hair cell loss. Two weeks afte...
Autores principales: | Seist, Richard, Landegger, Lukas D., Robertson, Nahid G., Vasilijic, Sasa, Morton, Cynthia C., Stankovic, Konstantina M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180578/ https://www.ncbi.nlm.nih.gov/pubmed/34108864 http://dx.doi.org/10.3389/fnmol.2021.670013 |
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