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Formulation of sublingual promethazine hydrochloride tablets for rapid relief of motion sickness

The delivery of antihistaminic agents via the oral route is problematic, especially for elderly patients. This study aimed to develop a sublingual formulation of promethazine hydrochloride by direct compression, and to mask its intensely bitter taste. Promethazine hydrochloride (PMZ) sublingual tabl...

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Detalles Bibliográficos
Autores principales:	Alyami, Hamad S, Ibrahim, Mohamed A., Alyami, Mohammad H., Dahmash, Eman Z, Almeanazel, Osaid T., Algahtani, Thamer S, Alanazi, Fars, Alshora, Doaa H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180616/ https://www.ncbi.nlm.nih.gov/pubmed/34135674 http://dx.doi.org/10.1016/j.jsps.2021.04.011

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