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Efficacy of the treatment for elderly emergency patients with sepsis

OBJECTIVES: We evaluated the impact of age in septic patients admitted through the ER on clinical outcome and cost. METHODS: Patients with sepsis admitted to the intensive care unit (ICU) through the emergency room in our hospital between January 2013 and December 2018 were analyzed. They were divid...

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Autores principales: Isshiki, Yuta, Nakajima, Jun, Sawada, Yusuke, Ichikawa, Yumi, Fukushima, Kazunori, Aramaki, Yuto, Oshima, Kiyohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180618/
https://www.ncbi.nlm.nih.gov/pubmed/34136701
http://dx.doi.org/10.1016/j.heliyon.2021.e07150
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author Isshiki, Yuta
Nakajima, Jun
Sawada, Yusuke
Ichikawa, Yumi
Fukushima, Kazunori
Aramaki, Yuto
Oshima, Kiyohiro
author_facet Isshiki, Yuta
Nakajima, Jun
Sawada, Yusuke
Ichikawa, Yumi
Fukushima, Kazunori
Aramaki, Yuto
Oshima, Kiyohiro
author_sort Isshiki, Yuta
collection PubMed
description OBJECTIVES: We evaluated the impact of age in septic patients admitted through the ER on clinical outcome and cost. METHODS: Patients with sepsis admitted to the intensive care unit (ICU) through the emergency room in our hospital between January 2013 and December 2018 were analyzed. They were divided into three groups according to their age: <65 years (group Y); 65–79 years (group M); and ≥80 years (group E). The duration of ICU and hospital stay, prognosis, and total hospital costs were compared among the three groups. RESULTS: During this period, 1,392 patients were admitted to the ICU through the emergency room, and 174 patients with sepsis were analyzed. There were 49, 79, and 46 patients in groups Y, M, and E, respectively. There was no significant difference in ICU stay. Group E exhibited the shortest hospital stay and the lowest total hospital cost with statistically significant difference (p = 0.010 and p = 0.007, respectively). However, group E showed the highest rate of hospital mortality (30.4%) compared to groups Y and M (14.3% and 21.5%, respectively; p = 0.163). CONCLUSIONS: Elderly (aged ≥80 years) emergency patients with sepsis require shorter hospital stay and are associated with lower total hospital cost. However, it may be difficult for these patients to maintain the hospital mortality equivalent to those observed in patients aged <80 years.
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spelling pubmed-81806182021-06-15 Efficacy of the treatment for elderly emergency patients with sepsis Isshiki, Yuta Nakajima, Jun Sawada, Yusuke Ichikawa, Yumi Fukushima, Kazunori Aramaki, Yuto Oshima, Kiyohiro Heliyon Research Article OBJECTIVES: We evaluated the impact of age in septic patients admitted through the ER on clinical outcome and cost. METHODS: Patients with sepsis admitted to the intensive care unit (ICU) through the emergency room in our hospital between January 2013 and December 2018 were analyzed. They were divided into three groups according to their age: <65 years (group Y); 65–79 years (group M); and ≥80 years (group E). The duration of ICU and hospital stay, prognosis, and total hospital costs were compared among the three groups. RESULTS: During this period, 1,392 patients were admitted to the ICU through the emergency room, and 174 patients with sepsis were analyzed. There were 49, 79, and 46 patients in groups Y, M, and E, respectively. There was no significant difference in ICU stay. Group E exhibited the shortest hospital stay and the lowest total hospital cost with statistically significant difference (p = 0.010 and p = 0.007, respectively). However, group E showed the highest rate of hospital mortality (30.4%) compared to groups Y and M (14.3% and 21.5%, respectively; p = 0.163). CONCLUSIONS: Elderly (aged ≥80 years) emergency patients with sepsis require shorter hospital stay and are associated with lower total hospital cost. However, it may be difficult for these patients to maintain the hospital mortality equivalent to those observed in patients aged <80 years. Elsevier 2021-05-28 /pmc/articles/PMC8180618/ /pubmed/34136701 http://dx.doi.org/10.1016/j.heliyon.2021.e07150 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Article
Isshiki, Yuta
Nakajima, Jun
Sawada, Yusuke
Ichikawa, Yumi
Fukushima, Kazunori
Aramaki, Yuto
Oshima, Kiyohiro
Efficacy of the treatment for elderly emergency patients with sepsis
title Efficacy of the treatment for elderly emergency patients with sepsis
title_full Efficacy of the treatment for elderly emergency patients with sepsis
title_fullStr Efficacy of the treatment for elderly emergency patients with sepsis
title_full_unstemmed Efficacy of the treatment for elderly emergency patients with sepsis
title_short Efficacy of the treatment for elderly emergency patients with sepsis
title_sort efficacy of the treatment for elderly emergency patients with sepsis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180618/
https://www.ncbi.nlm.nih.gov/pubmed/34136701
http://dx.doi.org/10.1016/j.heliyon.2021.e07150
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