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p-Nitrophenyl esters provide new insights and applications for the thiolase enzyme OleA
The OleA enzyme is distinct amongst thiolase enzymes in binding two long (≥C(8)) acyl chains into structurally-opposed hydrophobic channels, denoted A and B, to carry out a non-decarboxylative Claisen condensation reaction and initiate the biosynthesis of membrane hydrocarbons and β-lactone natural...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180931/ https://www.ncbi.nlm.nih.gov/pubmed/34141132 http://dx.doi.org/10.1016/j.csbj.2021.05.031 |