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Application of CRISPR-Cas9 gene editing for congenital heart disease

Clustered regularly interspaced short palindromic repeats and CRISPR-associated protein 9 (CRISPR-Cas9) is an ancient prokaryotic defense system that precisely cuts foreign genomic DNA under the control of a small number of guide RNAs. The CRISPR-Cas9 system facilitates efficient double-stranded DNA...

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Detalles Bibliográficos
Autores principales: Seok, Heeyoung, Deng, Rui, Cowan, Douglas B., Wang, Da-Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Pediatric Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8181018/
https://www.ncbi.nlm.nih.gov/pubmed/33677855
http://dx.doi.org/10.3345/cep.2020.02096