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Melatonin inhibits lipid accumulation to repress prostate cancer progression by mediating the epigenetic modification of CES1

BACKGROUND: Androgen deprivation therapy (ADT) is the main clinical treatment for patients with advanced prostate cancer (PCa). However, PCa eventually progresses to castration‐resistant prostate cancer (CRPC), largely because of androgen receptor variation and increased intratumoral androgen synthe...

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Detalles Bibliográficos
Autores principales: Zhou, Lijie, Zhang, Cai, Yang, Xiong, Liu, Lilong, Hu, Junyi, Hou, Yaxin, Tao, Hong, Sugimura, Haruhiko, Chen, Zhaohui, Wang, Liang, Chen, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8181204/
https://www.ncbi.nlm.nih.gov/pubmed/34185414
http://dx.doi.org/10.1002/ctm2.449

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