Cargando…
miR-373 Suppresses Cell Proliferation and Apoptosis via Regulation of SIRT1/PGC-1α/NRF2 Axis in Pancreatic Cancer
OBJECTIVE: Our study aimed to investigate function and mechanism of miR-373 in proliferation and apoptosis of pancreatic cancer (PC) cells by regulating NAD+-dependent histone deacetylase sirtulin 1 (SIRT1). MATERIALS AND METHODS: This experimental study included two PC cell lines AsPC-1 and PANC-1...
Autores principales: | Yin, Qing-Hua, Zhou, Yuan, Li, Zhi-Yuan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royan Institute
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8181315/ https://www.ncbi.nlm.nih.gov/pubmed/34096221 http://dx.doi.org/10.22074/cellj.2021.7038 |
Ejemplares similares
-
MiR-373 drives the epithelial-to-mesenchymal transition and metastasis via the miR-373-TXNIP-HIF1α-TWIST signaling axis in breast cancer
por: Chen, De, et al.
Publicado: (2015) -
Adiponectin promotes pancreatic cancer progression by inhibiting apoptosis via the activation of AMPK/Sirt1/PGC-1α signaling
por: Huang, Bingqing, et al.
Publicado: (2014) -
BMAL1 regulates mitochondrial homeostasis in renal ischaemia‐reperfusion injury by mediating the SIRT1/PGC‐1α axis
por: Ye, Peng, et al.
Publicado: (2022) -
∆nFGF1 Protects β-Cells against High Glucose-Induced Apoptosis via the AMPK/SIRT1/PGC-1α Axis
por: Chen, Qiong, et al.
Publicado: (2022) -
Rev1 contributes to proper mitochondrial function via the PARP-NAD(+)-SIRT1-PGC1α axis
por: Fakouri, Nima Borhan, et al.
Publicado: (2017)