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miR-373 Suppresses Cell Proliferation and Apoptosis via Regulation of SIRT1/PGC-1α/NRF2 Axis in Pancreatic Cancer

OBJECTIVE: Our study aimed to investigate function and mechanism of miR-373 in proliferation and apoptosis of pancreatic cancer (PC) cells by regulating NAD+-dependent histone deacetylase sirtulin 1 (SIRT1). MATERIALS AND METHODS: This experimental study included two PC cell lines AsPC-1 and PANC-1...

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Detalles Bibliográficos
Autores principales: Yin, Qing-Hua, Zhou, Yuan, Li, Zhi-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8181315/
https://www.ncbi.nlm.nih.gov/pubmed/34096221
http://dx.doi.org/10.22074/cellj.2021.7038

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