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Dexmedetomidine Inhibits ASIC Activity via Activation of α(2A) Adrenergic Receptors in Rat Dorsal Root Ganglion Neurons
Dexmedetomidine (DEX), a selective α(2) adrenergic receptor (α(2)-AR) agonist, has been shown to have peripheral analgesic effects in a variety of pain conditions. However, the precise molecular mechanisms have not yet been fully elucidated. Acid sensing ion channels (ASICs) are the major player in...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8181722/ https://www.ncbi.nlm.nih.gov/pubmed/34108881 http://dx.doi.org/10.3389/fphar.2021.685460 |