Increased myofibroblasts in the small airways, and relationship to remodelling and functional changes in smokers and COPD patients: potential role of epithelial–mesenchymal transition

INTRODUCTION: Previous reports have shown epithelial–mesenchymal transition (EMT) as an active process that contributes to small airway fibrotic pathology. Myofibroblasts are highly active pro-fibrotic cells that secrete excessive and altered extracellular matrix (ECM). Here we relate small airway m...

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Detalles Bibliográficos
Autores principales: Eapen, Mathew Suji, Lu, Wenying, Hackett, Tillie L., Singhera, Gurpreet Kaur, Mahmood, Malik Q., Hardikar, Ashutosh, Ward, Chris, Walters, Eugene Haydn, Sohal, Sukhwinder Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8181830/
https://www.ncbi.nlm.nih.gov/pubmed/34109247
http://dx.doi.org/10.1183/23120541.00876-2020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8181830/
https://www.ncbi.nlm.nih.gov/pubmed/34109247
http://dx.doi.org/10.1183/23120541.00876-2020

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