A C-circle assay for detection of alternative lengthening of telomere activity in FFPE tissue

Alternative lengthening of telomeres (ALT) is a telomerase-independent, recombination-based telomere maintenance mechanism that allows cancer cells to acquire unlimited proliferative capacity. The C-circle assay (CCA) has emerged as the gold standard for quantitative measurement of ALT activity. Her...

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Detalles Bibliográficos
Autores principales: Idilli, Aurora I., Segura-Bayona, Sandra, Lippert, Timothy P., Boulton, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8182116/
https://www.ncbi.nlm.nih.gov/pubmed/34136834
http://dx.doi.org/10.1016/j.xpro.2021.100569

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