Immunoglobulin G-4-Related Retroperitoneal Fibrosis

Retroperitoneal fibrosis is caused by the replacement of normal retroperitoneal tissue with fibrosis. The majority of the cases are idiopathic, but some secondary causes include malignancy, infection, drugs, and radiotherapy. Immunoglobulin G-4 (IgG-4) related disease is a relatively newer disease a...

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Autores principales: Huda, Syed Arqum, Kahlown, Sara Akram, Elder, Rachel, Kaul, Viren, Landsberg, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8182217/
https://www.ncbi.nlm.nih.gov/pubmed/34088232
http://dx.doi.org/10.1177/23247096211022487
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author Huda, Syed Arqum
Kahlown, Sara Akram
Elder, Rachel
Kaul, Viren
Landsberg, David
author_facet Huda, Syed Arqum
Kahlown, Sara Akram
Elder, Rachel
Kaul, Viren
Landsberg, David
author_sort Huda, Syed Arqum
collection PubMed
description Retroperitoneal fibrosis is caused by the replacement of normal retroperitoneal tissue with fibrosis. The majority of the cases are idiopathic, but some secondary causes include malignancy, infection, drugs, and radiotherapy. Immunoglobulin G-4 (IgG-4) related disease is a relatively newer disease and one of the rarer causes of retroperitoneal fibrosis. It usually involves the pancreas, lungs, kidneys, aorta lacrimal and salivary glands, or extrapancreatic bile duct. Elevated serum IgG-4 is the biomarker of the disease and its levels correlate with disease activity. High-dose glucocorticoid is the treatment of choice.
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spelling pubmed-81822172021-06-21 Immunoglobulin G-4-Related Retroperitoneal Fibrosis Huda, Syed Arqum Kahlown, Sara Akram Elder, Rachel Kaul, Viren Landsberg, David J Investig Med High Impact Case Rep Case Report Retroperitoneal fibrosis is caused by the replacement of normal retroperitoneal tissue with fibrosis. The majority of the cases are idiopathic, but some secondary causes include malignancy, infection, drugs, and radiotherapy. Immunoglobulin G-4 (IgG-4) related disease is a relatively newer disease and one of the rarer causes of retroperitoneal fibrosis. It usually involves the pancreas, lungs, kidneys, aorta lacrimal and salivary glands, or extrapancreatic bile duct. Elevated serum IgG-4 is the biomarker of the disease and its levels correlate with disease activity. High-dose glucocorticoid is the treatment of choice. SAGE Publications 2021-06-04 /pmc/articles/PMC8182217/ /pubmed/34088232 http://dx.doi.org/10.1177/23247096211022487 Text en © 2021 American Federation for Medical Research https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Huda, Syed Arqum
Kahlown, Sara Akram
Elder, Rachel
Kaul, Viren
Landsberg, David
Immunoglobulin G-4-Related Retroperitoneal Fibrosis
title Immunoglobulin G-4-Related Retroperitoneal Fibrosis
title_full Immunoglobulin G-4-Related Retroperitoneal Fibrosis
title_fullStr Immunoglobulin G-4-Related Retroperitoneal Fibrosis
title_full_unstemmed Immunoglobulin G-4-Related Retroperitoneal Fibrosis
title_short Immunoglobulin G-4-Related Retroperitoneal Fibrosis
title_sort immunoglobulin g-4-related retroperitoneal fibrosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8182217/
https://www.ncbi.nlm.nih.gov/pubmed/34088232
http://dx.doi.org/10.1177/23247096211022487
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AT landsbergdavid immunoglobuling4relatedretroperitonealfibrosis

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