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Blood RNA signature RISK4LEP predicts leprosy years before clinical onset
BACKGROUND: Leprosy, a chronic infectious disease caused by Mycobacterium leprae, is often late- or misdiagnosed leading to irreversible disabilities. Blood transcriptomic biomarkers that prospectively predict those who progress to leprosy (progressors) would allow early diagnosis, better treatment...
Autores principales: | Tió-Coma, Maria, Kiełbasa, Szymon M., van den Eeden, Susan J.F., Mei, Hailiang, Roy, Johan Chandra, Wallinga, Jacco, Khatun, Marufa, Soren, Sontosh, Chowdhury, Abu Sufian, Alam, Khorshed, van Hooij, Anouk, Richardus, Jan Hendrik, Geluk, Annemieke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8182229/ https://www.ncbi.nlm.nih.gov/pubmed/34090257 http://dx.doi.org/10.1016/j.ebiom.2021.103379 |
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