Reprogramming of the Caseinolytic Protease by ADEP Antibiotics: Molecular Mechanism, Cellular Consequences, Therapeutic Potential

Rising antibiotic resistance urgently calls for the discovery and evaluation of novel antibiotic classes and unique antibiotic targets. The caseinolytic protease Clp emerged as an unprecedented target for antibiotic therapy 15 years ago when it was observed that natural product-derived acyldepsipept...

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Detalles Bibliográficos
Autores principales: Brötz-Oesterhelt, Heike, Vorbach, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8182300/
https://www.ncbi.nlm.nih.gov/pubmed/34109219
http://dx.doi.org/10.3389/fmolb.2021.690902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8182300/
https://www.ncbi.nlm.nih.gov/pubmed/34109219
http://dx.doi.org/10.3389/fmolb.2021.690902

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