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Identification of the core motif of the BRCA2 C-terminal RAD51-binding domain by comparing canine and human BRCA2
Mammary tumors are the most common tumors in women and non-spayed female dogs. One of the reasons for mammary tumors is mutations of the tumor suppressor gene, BRCA2. BRCA2 participates in homologous recombination repair by interacting with the RAD51 recombinase. BRCA2 has two RAD51-binding domains,...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Japanese Society of Veterinary Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8182314/ https://www.ncbi.nlm.nih.gov/pubmed/33731496 http://dx.doi.org/10.1292/jvms.21-0006 |