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Supportive care for patients with brain metastases from lung cancer

Lung cancer is the most common cause of intracranial metastases (ICM). Metastases in the brain can result in a broad range of uncomfortable symptoms and significant morbidity secondary to neurological disability. Treatment options can range from surgical resection of solitary metastases to radiother...

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Detalles Bibliográficos
Autores principales: Sharma, Akanksha, Mrugala, Maciej M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8182494/
https://www.ncbi.nlm.nih.gov/pubmed/34164218
http://dx.doi.org/10.21037/jtd-2019-rbmlc-11
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author Sharma, Akanksha
Mrugala, Maciej M.
author_facet Sharma, Akanksha
Mrugala, Maciej M.
author_sort Sharma, Akanksha
collection PubMed
description Lung cancer is the most common cause of intracranial metastases (ICM). Metastases in the brain can result in a broad range of uncomfortable symptoms and significant morbidity secondary to neurological disability. Treatment options can range from surgical resection of solitary metastases to radiotherapy and more recently systemic targeted therapies and immunotherapy. Patient survival continues to improve with innovations made in treatments for this condition, but each of these treatments carry their own adverse effects that must be appropriately managed. These patients can benefit greatly from multidisciplinary care throughout the course of their disease. Clinicians involved in their care must be equipped with the ability to communicate skillfully and compassionately and set expectations for the road ahead, including symptoms, treatment plans, and prognosis. Involvement of a palliative care team can be very helpful, especially for patients who are nearing the terminal stages of the disease. Palliative care skills may be invaluable in the management of symptoms and can ease suffering for patients and their caregivers, thus allowing for maximum quality of life for as long as possible. End of life may bring its own complications and challenges; and opinion of an experienced and knowledgeable clinician can alleviate the pain and distress of the patient and also bring peace to the caregivers and loved ones.
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spelling pubmed-81824942021-06-22 Supportive care for patients with brain metastases from lung cancer Sharma, Akanksha Mrugala, Maciej M. J Thorac Dis Review Article on Radiotherapy for Brain Metastases from Lung Cancer Lung cancer is the most common cause of intracranial metastases (ICM). Metastases in the brain can result in a broad range of uncomfortable symptoms and significant morbidity secondary to neurological disability. Treatment options can range from surgical resection of solitary metastases to radiotherapy and more recently systemic targeted therapies and immunotherapy. Patient survival continues to improve with innovations made in treatments for this condition, but each of these treatments carry their own adverse effects that must be appropriately managed. These patients can benefit greatly from multidisciplinary care throughout the course of their disease. Clinicians involved in their care must be equipped with the ability to communicate skillfully and compassionately and set expectations for the road ahead, including symptoms, treatment plans, and prognosis. Involvement of a palliative care team can be very helpful, especially for patients who are nearing the terminal stages of the disease. Palliative care skills may be invaluable in the management of symptoms and can ease suffering for patients and their caregivers, thus allowing for maximum quality of life for as long as possible. End of life may bring its own complications and challenges; and opinion of an experienced and knowledgeable clinician can alleviate the pain and distress of the patient and also bring peace to the caregivers and loved ones. AME Publishing Company 2021-05 /pmc/articles/PMC8182494/ /pubmed/34164218 http://dx.doi.org/10.21037/jtd-2019-rbmlc-11 Text en 2021 Journal of Thoracic Disease. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Review Article on Radiotherapy for Brain Metastases from Lung Cancer
Sharma, Akanksha
Mrugala, Maciej M.
Supportive care for patients with brain metastases from lung cancer
title Supportive care for patients with brain metastases from lung cancer
title_full Supportive care for patients with brain metastases from lung cancer
title_fullStr Supportive care for patients with brain metastases from lung cancer
title_full_unstemmed Supportive care for patients with brain metastases from lung cancer
title_short Supportive care for patients with brain metastases from lung cancer
title_sort supportive care for patients with brain metastases from lung cancer
topic Review Article on Radiotherapy for Brain Metastases from Lung Cancer
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8182494/
https://www.ncbi.nlm.nih.gov/pubmed/34164218
http://dx.doi.org/10.21037/jtd-2019-rbmlc-11
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